Foerster-Bernstein Fellow 2017-18: Anne Marie Augustus, PhD

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Anne Marie earned her BS in Biochemistry and Linguistics from Arizona State University and her PhD in Biochemistry from Duke University. Currently, she is working with Dr. Raluca Gordan using microarrays to study transcription factors and how they bind to DNA. She was previously a postdoctoral researcher with Dr. Nicolas Buchler, Duke University where she studied the evolution of proteins involved in cell cycle regulation in fungi and with Dr. Harold Erickson, Duke University where she studied FtsZ homologs in plant chloroplasts that are involved in organelle division. Her research interests include transcription regulation and regulatory networks, comparative genomics, and protein structure and function.

 

 

Mentor: Raluca Gordân, PhD, Assistant Professor of Biostatistics and Bioinformatics

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Raluca Gordân is a faculty member in the Department of Biostatistics and Bioinformatics. She received her PhD in Computer Science in 2009 from Duke University, where she worked on DNA motif discovery algorithms under the supervision of Prof. Alex Hartemink. Dr. Gordân conducted postdoctoral research with Prof. Martha Bulyk at Brigham & Women's Hospital and Harvard Medical School (Boston, MA), studying the DNA binding specificity of transcription factors using protein binding microarrays. Her training was supported by a postdoctoral fellowship from the American Heart Association. Dr. Gordân is particularly interested in the mechanisms by which transcription factors are recruited to their specific DNA sites, both in vitro and in vivo, and how this recruitment is affected by changes in the DNA or protein sequence. Her work uses protein binding microarray assays and computational approaches that combine different types of information relevant for DNA binding and transcriptional regulation.